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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EYA1
All Species:
18.79
Human Site:
Y344
Identified Species:
59.05
UniProt:
Q99502
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99502
NP_000494.2
592
64593
Y344
H
S
L
L
T
G
S
Y
A
N
R
Y
G
R
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849806
585
63912
S348
Y
G
R
D
P
P
T
S
V
S
L
G
L
R
M
Cat
Felis silvestris
Mouse
Mus musculus
P97767
591
64343
A344
S
L
L
T
G
S
Y
A
N
R
Y
G
R
D
P
Rat
Rattus norvegicus
XP_002729501
587
63925
G344
G
S
Y
A
N
R
Y
G
R
D
P
P
T
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506770
633
68678
Y385
H
S
L
L
T
G
S
Y
A
Q
K
Y
G
K
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001083888
592
64622
Y344
H
S
L
L
T
G
S
Y
A
N
R
Y
G
R
D
Zebra Danio
Brachydanio rerio
NP_571268
609
66497
Y361
H
S
L
L
T
G
S
Y
A
N
R
F
G
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q05201
766
80638
Y515
H
T
L
L
S
G
S
Y
A
N
R
Y
T
K
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
97.3
N.A.
94.9
96.1
N.A.
69.5
N.A.
92.5
85.5
N.A.
38.7
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
97.8
N.A.
97.4
97.4
N.A.
79.1
N.A.
96.1
91.4
N.A.
51.7
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
6.6
N.A.
6.6
6.6
N.A.
80
N.A.
100
93.3
N.A.
73.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
26.6
N.A.
6.6
13.3
N.A.
93.3
N.A.
100
100
N.A.
93.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
0
0
0
13
63
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
13
0
0
0
0
0
13
0
0
0
13
63
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% F
% Gly:
13
13
0
0
13
63
0
13
0
0
0
25
50
0
0
% G
% His:
63
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
13
0
0
25
0
% K
% Leu:
0
13
75
63
0
0
0
0
0
0
13
0
13
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% M
% Asn:
0
0
0
0
13
0
0
0
13
50
0
0
0
0
0
% N
% Pro:
0
0
0
0
13
13
0
0
0
0
13
13
0
0
13
% P
% Gln:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% Q
% Arg:
0
0
13
0
0
13
0
0
13
13
50
0
13
50
0
% R
% Ser:
13
63
0
0
13
13
63
13
0
13
0
0
0
13
0
% S
% Thr:
0
13
0
13
50
0
13
0
0
0
0
0
25
0
0
% T
% Val:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
0
13
0
0
0
25
63
0
0
13
50
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _